PARTICIPATE IN RESEARCH STUDIES
NSAID-HEAL
Targeting Interindividual Variability in NSAID Responses to Mitigate Chronic Pelvic Pain Risk in Dysmenorrhea
Who- Individuals ages 18-35 with regular menstrual cycles who have painful periods
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Why- This study explores whether NSAIDs, like naproxen sodium (Aleve), can not only relieve period pain now, but also reduce pain over time. These medications have been shown to be effective in helping people with menstrual and pelvic pain. However, the usage of these medications for menstrual pain has never been carefully studied over a full year at the recommended dose.
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When- Participation will take no more than 18 months.
Where- This study will involve both at-home participation and in-person visits at Evanston Hospital.
What- This study involves a12 month regimen that includes at-home hormone monitoring and taking a provided medication for several days during the participant's period. The provided study medication will be randomly assigned as either naproxen sodium (Aleve) or a placebo pill (also known as an inactive pill). In addition, participants will be asked to complete periodic virtual assessments and in-person visits to Evanston Hospital.
Compensation- Participants can receive up to $750 in compensation.
To participate, please click the link below to fill out our online prescreen.
You can also reach us at 847-570-2622 or at PelvicPainResearch@northshore.org.
MCUP
Mechanistic Characterization of Uterine Pain (MCUP)
Who- Individuals ages 18-45 with regular menstrual cycles who either have painful periods, uterine fibroids, endometriosis, or those with none of the above to participate as healthy controls. You cannot have an IUD to participate in this study
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Why- We hope to study the physiological cause of menstrual pain and learn why a common over the counter NSAID may or may not help with cramping pain
Where- Department of Gynecology at Evanston Hospital, right off the Central stop on the CTA Purple line
What- This study is observing how MRI technology can be used to learn more about painful periods, and how naproxen (Aleve) can help people manage their menstrual pain. The study involves 3 in-person visits: A 2-hour screen visit which will include filling out questionnaires and sensory tests, and 2 separate 4.5-hour MRI visits during your period that include taking either naproxen or a placebo drug. Participants must abstain from taking painkillers 8-12 hours before each MRI visit.
Compensation- Up to $350-375 compensation is possible.
To participate, please click the link below to fill out our online prescreen.
You can also reach us at 847-570-2622 or at PelvicPainResearch@northshore.org.
CRAMPP2
Cross Organ Mechanisms in Chronic Pelvic Pain (CRAMPP2)
Who- Individuals assigned female at birth, ages 18-35 with regular menstrual cycles with or without painful periods.
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Why- Our goal is to identify the mechanisms that cause pelvic pain, including painful periods, and prevent the development of chronic pain.
Where- Most participants will solely access their study assessments from their home via a laptop or tablet, while a select cohort will have the option for additional visits at Evanston Hospital (2650 Ridge Ave).
What- The study involves a short online diary during 5 days of an upcoming period, then a 2-3 hour virtual assessment once a year for 2 years (3 total assessments). These assessments will include questionnaires and a bladder filling task. As a token of our appreciation, we are offering compensation of $180.
Select participants will also be invited to participate in several in-person visits at Evanston Hospital. These visits are voluntary, and you can choose to participate in only the virtual assessments if you would like. The in-person visits offer up to $395 in additional compensation over 1 year. Additional details about the in-person visits will be available for those for qualify.
To participate, please click the link below to fill out our online eligibility screen. You can also visit our CRAMPP2 website - EvanstonPeriodStudy.com - to learn more!
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